| Title | Methodological issues in design and analysis of a matched case-control study of a vaccine's effectiveness. |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Niccolai, Linda M., Lorraine G. Ogden, Catherine E. Muehlenbein, James D. Dziura, Marietta Vázquez, and Eugene D. Shapiro |
| Journal | Journal of clinical epidemiology |
| Volume | 60 |
| Issue | 11 |
| Pagination | 1127-31 |
| Date Published | 2007 Nov |
| ISSN | 0895-4356 |
| Keywords | Age Factors, Case-Control Studies, Chickenpox Vaccine, Epidemiologic Research Design, Humans, Logistic Models, Odds Ratio, Patient Selection, Risk Assessment, Time Factors, Treatment Outcome |
| Abstract | Case-control studies of the effectiveness of a vaccine are useful to answer important questions, such as the effectiveness of a vaccine over time, that usually are not addressed by prelicensure clinical trials of the vaccine's efficacy. This report describes methodological issues related to design and analysis that were used to determine the effects of time since vaccination and age at the time of vaccination. |
| DOI | 10.1016/j.amepre.2011.06.032 |
| Alternate Journal | J Clin Epidemiol |
