| Title | Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Mannheimer, Sharon B., Nicholas Wold, Edward M. Gardner, Edward E. Telzak, Katherine Huppler Hullsiek, Margaret Chesney, Albert W. Wu, Rodger D. MacArthur, John Matts, and Gerald Friedland |
| Corporate Authors | Terry Beirn Community Programs for Clinical Research on AIDS |
| Journal | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| Volume | 46 |
| Issue | 6 |
| Pagination | 941-5 |
| Date Published | 2008 Mar 15 |
| ISSN | 1537-6591 |
| Keywords | Adult, Anti-HIV Agents, Drug Therapy, Combination, Female, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Male, Middle Aged, Quality of Life, Reverse Transcriptase Inhibitors, Severity of Illness Index, Treatment Outcome |
| Abstract | Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline. |
| DOI | 10.1086/528859 |
| Alternate Journal | Clin. Infect. Dis. |
