Title | Pharmacokinetic drug interactions and adverse consequences between psychotropic medications and pharmacotherapy for the treatment of opioid dependence. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Saber-Tehrani, Ali S., Robert Douglas Bruce, and Frederick L. Altice |
Journal | The American journal of drug and alcohol abuse |
Volume | 37 |
Issue | 1 |
Pagination | 1-11 |
Date Published | 2011 Jan |
ISSN | 1097-9891 |
Keywords | Drug Interactions, Humans, Narcotic Antagonists, Opioid-Related Disorders, Psychotropic Drugs |
Abstract | Psychiatric comorbidities among opioid-dependent patients are common. Many medications used to treat both conditions are metabolized through complimentary cytochrome P450 isoenzymes. When medication-assisted treatment for opioid dependence is concurrently used with psychotropic medications, problematic pharmacokinetic drug interactions may occur. |
DOI | 10.1007/s11904-011-0095-3 |
Alternate Journal | Am J Drug Alcohol Abuse |