Yale University

Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety.

TitleReduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety.
Publication TypeJournal Article
Year of Publication2015
AuthorsO'Malley, Stephanie S., William R. Corbin, Robert F. Leeman, Kelly S. DeMartini, Lisa M. Fucito, Jolomi Ikomi, Denise M. Romano, Ran Wu, Benjamin A. Toll, Kenneth J. Sher, Ralitza Gueorguieva, and Henry R. Kranzler
JournalThe Journal of clinical psychiatry
Volume76
Issue2
Paginatione207-13
Date Published2015 Feb
ISSN1555-2101
AbstractNaltrexone, an opioid antagonist, may facilitate reduction in drinking among young adults. We compared the efficacy and safety of naltrexone administered daily plus targeted dosing with placebo to reduce drinking in young adults who engage in heavy drinking.
DOI10.4088/JCP.13m08934
Alternate JournalJ Clin Psychiatry

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