| Title | Survival from XDR-TB is associated with modifiable clinical characteristics in rural South Africa. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Shenoi, Sheela V., Ralph P. Brooks, Russell Barbour, Frederick L. Altice, Daniel Zelterman, Anthony P. Moll, Iqbal Master, Theo L. van der Merwe, and Gerald H. Friedland |
| Journal | PloS one |
| Volume | 7 |
| Issue | 3 |
| Pagination | e31786 |
| Date Published | 2012 |
| ISSN | 1932-6203 |
| Keywords | Adult, Antiretroviral Therapy, Highly Active, Antitubercular Agents, Case-Control Studies, Coinfection, Extensively Drug-Resistant Tuberculosis, Female, HIV Infections, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Retrospective Studies, Risk Factors, South Africa |
| Abstract | Drug-resistant tuberculosis (TB) is a major threat to global public health. Patients with extensively drug-resistant TB (XDR-TB), particularly those with HIV-coinfection, experience high and accelerated mortality with limited available interventions. To determine modifiable factors associated with survival, we evaluated XDR-TB patients from a community-based hospital in rural South Africa where a large number of XDR-TB cases were first detected. |
| DOI | 10.1371/journal.pone.0031786 |
| Alternate Journal | PLoS ONE |
