| Title | Therapeutic response of HIV-1 subtype C in African patients coinfected with either Mycobacterium tuberculosis or human herpesvirus-8. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Cassol, Edana, Taryn Page, Anisa Mosam, Gerald Friedland, Chris Jack, Umesh Lalloo, Joe Kopetka, Bruce Patterson, Tonya Esterhuizen, and Hoosen M. Coovadia |
| Journal | The Journal of infectious diseases |
| Volume | 191 |
| Issue | 3 |
| Pagination | 324-32 |
| Date Published | 2005 Feb 1 |
| ISSN | 0022-1899 |
| Keywords | Adolescent, Adult, AIDS-Related Opportunistic Infections, Anti-HIV Agents, CD4 Lymphocyte Count, Drug Therapy, Combination, Female, Herpesvirus 8, Human, HIV Infections, HIV-1, Humans, Male, Middle Aged, Mycobacterium tuberculosis, Reverse Transcriptase Inhibitors, RNA, Viral, Sarcoma, Kaposi, Treatment Outcome, Tuberculosis, Pulmonary, Viral Load |
| Abstract | A potential confounding factor in the treatment of human immunodeficiency virus (HIV) infection in Africa is the frequent occurrence of opportunistic infections (OIs). OI-induced immune activation can interfere with HIV-1 clearance by increasing viral replication and target cell availability. |
| DOI | 10.3109/00952990.2011.568081 |
| Alternate Journal | J. Infect. Dis. |
