| Title | Association betweenTLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users. |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Huik, Kristi, Radko Avi, Merit Pauskar, Eveli Kallas, Ene-Ly Jõgeda, Tõnis Karki, Kristina Marsh, Don Des Jarlais, Anneli Uusküla, and Irja Lutsar |
| Journal | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
| Date Published | 2013 Aug 17 |
| ISSN | 1567-7257 |
| Abstract | TLR3 recognizes dsRNA and triggers immune responses against RNA and DNA viruses. A polymorphism in TLR3, rs3775291 (Leu412Phe), has been associated with the increased susceptibility to enteroviral myocarditis, protection against tick-borne encephalitis virus and HIV-1 infection. We investigated Caucasian intravenous drug users (IDUs) and blood donors in order to evaluate the associations between TLR3 genotypes and susceptibility to HIV infection. |
| DOI | 10.1111/milq.12017 |
| Alternate Journal | Infect. Genet. Evol. |
