Title | Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Barry, Oliver, Jonathan Powell, Lorna Renner, Evelyn Y. Bonney, Meghan Prin, William Ampofo, Jonas Kusah, Bamenla Goka, Kwamena W. C. Sagoe, Veronika Shabanova, and Elijah Paintsil |
Journal | BMC infectious diseases |
Volume | 13 |
Pagination | 476 |
Date Published | 2013 |
ISSN | 1471-2334 |
Keywords | Adolescent, Anti-HIV Agents, CD4-Positive T-Lymphocytes, Child, Child, Preschool, Drug Resistance, Viral, Female, Ghana, HIV Infections, HIV-1, Humans, Infant, Longitudinal Studies, Male, Prospective Studies, Treatment Outcome, Viral Load |
Abstract | Antiretroviral therapy (ART) scale-up in resource-limited countries, with limited capacity for CD4 and HIV viral load monitoring, presents a unique challenge. We determined the effectiveness of first-line ART in a real world pediatric HIV clinic and explored associations between readily obtainable patient data and the trajectories of change in CD4 count and HIV viral load. |
DOI | 10.1186/1471-2334-13-476 |
Alternate Journal | BMC Infect. Dis. |