Title | Efficacy and day 7 plasma piperaquine concentrations in african children treated for uncomplicated malaria with dihydroartemisinin-piperaquine. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Zongo, Issaka, Fabrice A. Somé, Serge A. M. Somda, Sunil Parikh, Noel Rouamba, Philip J. Rosenthal, Joel Tarning, Niklas Lindegardh, François Nosten, and Jean Bosco Ouédraogo |
Journal | PloS one |
Volume | 9 |
Issue | 8 |
Pagination | e103200 |
Date Published | 2014 |
ISSN | 1932-6203 |
Abstract | One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. |
DOI | 10.1371/journal.pone.0103200 |
Alternate Journal | PLoS ONE |