Title | Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. |
Publication Type | Journal Article |
Year of Publication | 2006 |
Authors | Gandhi, Neel R., Anthony Moll, Willem A. Sturm, Robert Pawinski, Thiloshini Govender, Umesh Lalloo, Kimberly Zeller, Jason Andrews, and Gerald Friedland |
Journal | Lancet |
Volume | 368 |
Issue | 9547 |
Pagination | 1575-80 |
Date Published | 2006 Nov 4 |
ISSN | 1474-547X |
Keywords | Adult, Aged, Anti-Retroviral Agents, Female, Genotype, HIV Infections, HIV-1, Humans, Male, Middle Aged, Mycobacterium tuberculosis, Population Surveillance, Prevalence, Rural Health, South Africa, Sputum, Tuberculosis, Multidrug-Resistant, Viral Load |
Abstract | The epidemics of HIV-1 and tuberculosis in South Africa are closely related. High mortality rates in co-infected patients have improved with antiretroviral therapy, but drug-resistant tuberculosis has emerged as a major cause of death. We assessed the prevalence and consequences of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis in a rural area in KwaZulu Natal, South Africa. |
DOI | 10.3109/00952990.2011.568081 |
Alternate Journal | Lancet |