Yale University

The HPV vaccine impact monitoring project (HPV-IMPACT): assessing early evidence of vaccination impact on HPV-associated cervical cancer precursor lesions.

TitleThe HPV vaccine impact monitoring project (HPV-IMPACT): assessing early evidence of vaccination impact on HPV-associated cervical cancer precursor lesions.
Publication TypeJournal Article
Year of Publication2012
AuthorsHariri, Susan, Elizabeth R. Unger, Suzanne E. Powell, Heidi M. Bauer, Nancy M. Bennett, Karen C. Bloch, Linda M. Niccolai, Sean Schafer, and Lauri E. Markowitz
Corporate AuthorsHPV-IMPACT Working Group
JournalCancer causes & control : CCC
Volume23
Issue2
Pagination281-8
Date Published2012 Feb
ISSN1573-7225
KeywordsAdenocarcinoma, Adolescent, Adult, Cervical Intraepithelial Neoplasia, Female, Genotype, Humans, Papillomaviridae, Papillomavirus Vaccines, Pilot Projects, Precancerous Conditions, Prospective Studies, Uterine Cervical Neoplasms, Young Adult
AbstractThe following paper describes a collaboration between the Centers for Disease Control and Prevention and five Emerging Infections Program sites to develop a comprehensive population-based approach to monitoring human papillomavirus (HPV) vaccine impact on cervical cancer precursors and associated HPV genotypes. The process of establishing this novel monitoring system is described, and development details such as enumeration of sources for reporting cervical intraepithelial neoplasia 2/3 and adenocarcinoma in situ, approaches to case ascertainment, electronic reporting, and HPV typing are outlined. Implementation of a feasible and sustainable surveillance system for HPV-associated cervical precancers will enable evaluation of the direct impact of HPV vaccination.
DOI10.1007/s10552-011-9877-6
Alternate JournalCancer Causes Control

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