| Title | The relationship of preventable opportunistic infections, HIV-1 RNA, and CD4 Cell counts to chronic mortality. |
| Publication Type | Journal Article |
| Year of Publication | 2002 |
| Authors | Seage, George R., Elena Losina, Sue J. Goldie, David A. Paltiel, April D. Kimmel, and Kenneth A. Freedberg |
| Journal | Journal of acquired immune deficiency syndromes (1999) |
| Volume | 30 |
| Issue | 4 |
| Pagination | 421-8 |
| Date Published | 2002 Aug 1 |
| ISSN | 1525-4135 |
| Keywords | Adult, AIDS-Related Opportunistic Infections, CD4 Lymphocyte Count, Cohort Studies, HIV Infections, HIV-1, Humans, Male, Proportional Hazards Models, RNA, Viral, United States |
| Abstract | Both HIV-1 RNA and absolute CD4 cell counts have been identified as important predictors of HIV-1 disease progression and mortality. The independent impact of opportunistic infections on the risk of chronic mortality, defined as death beyond 30 days of an opportunistic infection, has not been studied when controlling for HIV-1 RNA. Our objective was to determine the relationship between a history of any of five preventable opportunistic infections (Pneumocystis carinii pneumonia, Mycobacterium avium complex, toxoplasmosis, cytomegalovirus, and candida esophagitis) and chronic mortality. |
| DOI | 10.1111/j.1524-4733.2010.00763.x |
| Alternate Journal | J. Acquir. Immune Defic. Syndr. |
