| Title | Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Walensky, Rochelle P., Robin Wood, Andrea L. Ciaranello, David A. Paltiel, Sarah B. Lorenzana, Xavier Anglaret, Adam W. Stoler, and Kenneth A. Freedberg |
| Corporate Authors | CEPAC-International Investigators |
| Journal | PLoS medicine |
| Volume | 7 |
| Issue | 12 |
| Pagination | e1000382 |
| Date Published | 2010 |
| ISSN | 1549-1676 |
| Keywords | Acquired Immunodeficiency Syndrome, Adult, Anti-HIV Agents, Cost-Benefit Analysis, Female, Guidelines as Topic, HIV Infections, Humans, Male, Models, Theoretical, World Health Organization, Young Adult |
| Abstract | The new 2010 World Health Organization (WHO) HIV treatment guidelines recommend earlier antiretroviral therapy (ART) initiation (CD4<350 cells/µl instead of CD4<200 cells/µl), multiple sequential ART regimens, and replacement of first-line stavudine with tenofovir. This paper considers what to do first in resource-limited settings where immediate implementation of all of the WHO recommendations is not feasible. |
| DOI | 10.1371/journal.pmed.1000382 |
| Alternate Journal | PLoS Med. |
