| Title | The potential impact of a moderately effective HIV vaccine with rapidly waning protection in South Africa and Thailand. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Andersson, Kyeen M., and John Stover |
| Journal | Vaccine |
| Volume | 29 |
| Issue | 36 |
| Pagination | 6092-9 |
| Date Published | 2011 Aug 18 |
| ISSN | 1873-2518 |
| Keywords | Adolescent, Adult, AIDS Vaccines, Clinical Trials as Topic, Computer Simulation, Female, HIV, HIV Infections, Humans, Immunization Programs, Male, Middle Aged, Models, Theoretical, Sex Workers, South Africa, Thailand, Time Factors, Treatment Outcome, Vaccination, Young Adult |
| Abstract | Although published data from the recent ALVAC/AIDSVAX trial in Thailand (RV144) indicated the HIV vaccine provided very modest protection overall (31.2%), new analysis of trial data has suggested higher efficacy levels earlier in the follow-up period. CDC and UNAIDS organized several modeling research teams to explore the implications of the trial results and potential utility of this vaccine. |
| DOI | 10.1097/QAI.0b013e3181fbc94f |
| Alternate Journal | Vaccine |
