Yale University

Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population.

TitleAssociation between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population.
Publication TypeJournal Article
Year of Publication2014
AuthorsHuik, Kristi, Radko Avi, Helen Uibopuu, Merit Pauskar, Tõnu Margus, Tõnis Karki, Tõnu Krispin, Piret Kool, Kristi Rüütel, Ave Talu, Katri Abel-Ollo, Anneli Uusküla, Andrew Carrillo, Weijing He, Sunil K. Ahuja, and Irja Lutsar
JournalJournal of acquired immune deficiency syndromes (1999)
Volume66
Issue3
Pagination239-44
Date Published2014 Jul 1
ISSN1944-7884
KeywordsAdult, Cross-Sectional Studies, Estonia, European Continental Ancestry Group, Female, Genetic Association Studies, Genetic Predisposition to Disease, Haplotypes, HIV Infections, HIV-1, Humans, Logistic Models, Male, Phylogeny, Polymorphism, Single Nucleotide, Receptors, CCR5, Viral Tropism, Young Adult
AbstractThe influence of the diversity of CCR5 on HIV susceptibility and disease progression has been clearly demonstrated but how the variability of this gene influences the HIV tropism is poorly understood. We investigated whether CCR5 haplotypes are associated with HIV tropism in a Caucasian population.
DOI10.1097/QAI.0000000000000127
Alternate JournalJ. Acquir. Immune Defic. Syndr.

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