Title | Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population. |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Huik, Kristi, Radko Avi, Helen Uibopuu, Merit Pauskar, Tõnu Margus, Tõnis Karki, Tõnu Krispin, Piret Kool, Kristi Rüütel, Ave Talu, Katri Abel-Ollo, Anneli Uusküla, Andrew Carrillo, Weijing He, Sunil K. Ahuja, and Irja Lutsar |
Journal | Journal of acquired immune deficiency syndromes (1999) |
Volume | 66 |
Issue | 3 |
Pagination | 239-44 |
Date Published | 2014 Jul 1 |
ISSN | 1944-7884 |
Keywords | Adult, Cross-Sectional Studies, Estonia, European Continental Ancestry Group, Female, Genetic Association Studies, Genetic Predisposition to Disease, Haplotypes, HIV Infections, HIV-1, Humans, Logistic Models, Male, Phylogeny, Polymorphism, Single Nucleotide, Receptors, CCR5, Viral Tropism, Young Adult |
Abstract | The influence of the diversity of CCR5 on HIV susceptibility and disease progression has been clearly demonstrated but how the variability of this gene influences the HIV tropism is poorly understood. We investigated whether CCR5 haplotypes are associated with HIV tropism in a Caucasian population. |
DOI | 10.1097/QAI.0000000000000127 |
Alternate Journal | J. Acquir. Immune Defic. Syndr. |